The founders probably never imagined airplanes flying into buildings or trucks killing a hundred at a time either.
Frankly, I'm not a fan of "the founders didn't imagine" arguments on any issue. First, it's almost always raised as a justification for not enforcing part of the Constitution or at least blunting its enforcement. Whether that's stated expressly or impliedly, that's the argument.
Second, that kind of argument is almost always applied selectively. How many people who raise this argument about machine guns or assault rifles bring up the fact that the founders likely didn't anticipate internet porn and gay marriage when they authored the First and Fourteenth Amendments? Pretty much none. Hell, did the founders anticipate that we'd be having serious arguments over issues like "what is a family?" or "what is a man/woman?"
Third, in the case of the Second Amendment, it's not a very strong point anyway. Did the founders foresee machine guns? Probably not, but did they foresee that weapons get stronger and more efficient with technology? Undoubtedly. Muskets look primitive today. They were advanced weapons in the 18th century - much moreso than the slings and bows and arrows that were used by previous generations. The founders were smart guys. They probably could see the pattern.
Finally, the founders were smart enough to know that they couldn't anticipate the issues of the future, which is why they developed an amendment process. If we want to weaken gun rights or any constitutional rights, then let's follow that process rather than depart from the rule of written law that so many advocate.
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