It's all I carry, but I travel weekly. Some pretty good deals at the Tumi outlet in San Marcos. There's a high quality less expensive line called Tumi Tech that you may check out.
The airline crews have used Purdy Neat Stuff for years. Durable and guaranteed. I used one bag for over 15 years and had to have one zipper repaired. Check out their "stuff".
Tumi (to me) is great and worth the money. I routinely travel 150k+ miles/year for work, and my Tumi has been a trooper over the last 3 years. Compare that to my first suitcase I bought out of college which lasted 5 round trips.
I decided to go for it with Tumi. They have a sale ($100 off for a $300 purchase). I bought an airport friendly laptop bag and wheeled carry-on garment bag. Love them both. I fly roundtrip from Los Angeles to Chicago each week (how I justified spending alot for luggage).